Letter to the Editor

COVID-19 Pandemic-are the Biggest Challenge Yet?


  • Burak Katipoğlu
  • Milosz Jaguszewski
  • Michal Pruc
  • Dorota Sagan
  • Lukasz Szarpak

Received Date: 17.09.2021 Accepted Date: 09.11.2021 Eurasian J Emerg Med 2022;21(4):285-286

Keywords: SARS-CoV-2, COVID-19, pandemic

Dear Editor,

The Coronavirus disease-2019 (COVID-19) pandemic is a huge challenge for both the health service and the society struggling with the disease (1,2). However, it is necessary to look at COVID-19 more broadly, not only from the perspective of hospitalization but also with patients after COVID-19 who come to us. To date, chronic symptoms such as fatigue, “brain fog”, depression, shortness of breath, cough, and muscle and joint pain have been commonly reported (3). The best known ones were those from the respiratory system, showing long-term damage to the lung tissue. The latest studies also found a 5-fold high risk of Guillain-Barré syndrome and an 11-fold high risk of encephalomyelitis in people having COVID-19, which may lead to further complications in the future (4). COVID-19 also significantly increases the risk of the first heart attack (three to eight times) and the first stroke (three to six times). According to the study, the risk gradually decreased but remained elevated for at least four weeks. Importantly, the study excluded people who had previously had a heart attack or stroke, which may suggest that the risk of another heart attack or stroke is significantly higher (5). Attention should also be paid to the incidence of myocarditis, which is 16 times higher in people with COVID-19, and the incidence of myocarditis in COVID-19 has been estimated at 150 per 100,000 patients. The inflammation of the heart muscle can lead to dysfunction of parts of the heart and increase the risk of heart failure (6). A study involving COVID-19 survivors with symptoms lasting at least 30 days found that around 5% of them experienced at least a 30% decrease in a critical measure of kidney function estimated glomerular filtration rate (eGFR). This study shows that people with long-COVID-19 were 25% more likely to develop a 30% decline in eGFR (7). Currently, LONG-COVID-19 syndrome occurs in 5% of vaccinated patients and 11% of the unvaccinated group (8). Patients after COVID-19 will come to us more often, especially with such a high percentage of virus infection. The only limitation to the incidence of complications is the vaccination. We should pay special attention to the function of the cardiovascular, kidney and respiratory systems, as well as consider creating an algorithm for managing patients with POST-COVID-19 and screening the public in primary care points.


Peer-review: Externally peer-reviewed.

Authorship Contributions

Concept - Design - Data Collection or Processing - Analysis or Interpretation - Literature Search - Writing: B.K., M.J., M.P., D.S., L.S.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study received no financial support.

  1. Krasiński Z, Chou A, Stępak H. COVID, long flights, and deep vein thrombosis: What we know so far. Cardiol J. 2021;28:941-53.
  2. Smereka J, Szarpak L, Filipiak KJ. Modern medicine in COVID-19 era. Disaster Emerg Med J. 2020;5:103-5.
  3. Dzieciatkowski T, Szarpak L, Filipiak KJ, Jaguszewski M, Ladny JR, Smereka J. COVID-19 challenge for modern medicine. Cardiol J. 2020;27:175-83.
  4. Li X, Martinez-Hernandez E, Herranz ER, Delmestri A, Salles TD, Strauss V, et al. Association between COVID-19 vaccination, infection, and risk of Guillain-Barre syndrome, Bell’s palsy, encephalomyelitis and transverse myelitis: a population-based cohort and self-controlled case series analysis. MedRxiv. 2021.09.08.21263276.
  5. Katsoularis I, Fonseca-Rodríguez O, Farrington P, Lindmark K, Fors Connolly AM. Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study, Lancet. 2021;398:599-607.
  6. Boehmer TK, Kompaniyets L, Lavery AM, Hsu J, Ko JY, Yusuf H, et al. Association Between COVID-19 and Myocarditis Using Hospital-Based Administrative Data - United States, March 2020-January 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1228-32.
  7. Bowe B, Xie Y, Xu E, Al-Aly Z. Kidney Outcomes in Long COVID. J Am Soc Nephrol. 2021;32:2851-62.
  8. Antonelli M, Penfold RS, Merino J, Sudre CH, Molteni E, Berry S, et al. Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study, Lancet Infect Dis. 2022;22:43-55.