Objective:
Esophageal stricture early corrosive burns to investigate the eff ectiveness in preventing the use of N-acetyl-cysteine. Strictures of the esophagus due to caustic substances occur with the ingestion of solid or liquid corrosive materials.
Materials and Methods:
A prospective randomized study was performed to evaluate the eff ectiveness of conventional therapy alone and conventional therapy + N-acetyl cysteine. Fifty patients with grade 2b and grade 3 burnt were analyzed. Intensive n-acetyl cysteine therapy can reduce the incidence of stricture development in patients with advanced grade corrosive esophagitis.
Results:
N-acetyl cysteine group+ Konvansitonel used in 1 patient, stenosis developed in 7 patients in the group with conventional treatment.
Conclusion:
We believe that our fi ndings will be better supported with the groups including larger number of patients or with the experimental studies.
Keywords: Esophagitis corrosıve, N-acetyl cysteine, stricture